More than a Toxin: Protein Inventory of Clostridium tetani Toxoid Vaccines
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چکیده
منابع مشابه
Continuous production of Clostridium tetani toxin.
The continuous production of Clostridium tetani toxin has been carried out in a 1-liter stirred culture vessel for as long as 65 days. Toxin production of approximately 120 flocculating units per ml was maintained with a dilution rate of 0.125 hr(-1), a temperature of 34 C, a pH of 7.4, and the addition to the medium of 0.1 g of potassium chloride per liter. The average minimal lethal intraperi...
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Clostridium tetani and Clostridium botulinum produce two of the most potent neurotoxins known, tetanus neurotoxin and botulinum neurotoxin, respectively. Extensive biochemical and genetic investigation has been devoted to identifying and characterizing various C. botulinum strains. Less effort has been focused on studying C. tetani likely because recently sequenced strains of C. tetani show muc...
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Clostridium tetani is generally considered to be a nonsaccharolytic organism and is so described in the most recent edition of Bergey's Manual of Determinative Bacteriology (Breed et al., 1957). Despite this widespread opinion, evidence to the contrary exists. Achalme (1902) reported the stimulation of growth of this organism by glucose without ferementation of glucose; Reddish and Rettger (192...
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Okadaic acid (OA) is one of the most frequent and worldwide distributed marine toxins. It is easily accumulated by shellfish, mainly bivalve mollusks and fish, and, subsequently, can be consumed by humans causing alimentary intoxications. OA is the main representative diarrheic shellfish poisoning (DSP) toxin and its ingestion induces gastrointestinal symptoms, although it is not considered let...
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ژورنال
عنوان ژورنال: Proteomes
سال: 2019
ISSN: 2227-7382
DOI: 10.3390/proteomes7020015